Free US shipping on orders $250+ · Research Use Only · 14-Day Risk-Free Guarantee
igf-1 lr3
IGF-1 LR3 is a recombinant analogue of Insulin-Like Growth Factor 1 with an N-terminal 13-amino acid extension and Arg→Gly substitution at position 3, reducing IGFBP binding and extending half-life. Preferred tool for in-vitro anabolic signaling research. Synthesized to >98% purity. For research use only.
$80.99
14-day risk-free guarantee · Free US shipping on orders $250+
COA / Batch Lookup
Search certificates of analysis by batch number
Get Started →
Dosage
1mg
Subscribe & Save
Buy 1
$80.99 each
$80.99
Most Popular
Buy 2 Save 5%
$76.94 each
$153.88
$161.98
Best Value
Buy 3+ Save 10%
$72.89 each
$218.67
$242.97
Subscribe & Save
Discounted per-vial pricing | No hidden fees
1
14-day risk-free guarantee · Secure checkout
Research Use Only — Not for Human Consumption
IGF-1 LR3 has been extensively studied in muscle and metabolic research contexts:
- Prolonged receptor activation vs. native IGF-1 due to reduced binding protein affinity in animal models
- Stimulates satellite cell proliferation and myofibril hypertrophy in skeletal muscle tissue studies
- Upregulates protein synthesis via PI3K/Akt/mTOR signaling in preclinical research
- Enhances glucose uptake in muscle cells independent of insulin in cell culture models
- Half-life reported at ~20–30 hours vs. ~12 minutes for native IGF-1 in preclinical studies
Every batch is independently tested by a US-based third-party laboratory. Our Certificate of Analysis confirms:
Search COA Library →
- Identity: confirmed by HPLC and mass spectrometry
- Purity: >98% by HPLC
- Endotoxin: <1 EU/mg
- Appearance: white to off-white lyophilized powder
Search COA Library →
- Baserga R. (1994). The insulin-like growth factor I receptor: a key to tumor growth? Cancer Res.
- Buerge M, et al. (2010). Increased anabolic signaling with IGF-1 LR3 in skeletal muscle. J Appl Physiol.
- Rinderknecht E, Humbel RE. (1978). The amino acid sequence of human insulin-like growth factor I. J Biol Chem.
Frequently Paired Compounds
Ipamorelin
GH Secretagogue
MOTS-c
Mitochondrial Peptide
BAC Water
Reconstitution Solution
meet the collection.
Made With
igf-1
growth factor · lr3 variant
IGF-1 LR3 is a recombinant analogue with Arg→Gly substitution at position 3 and a 13-amino acid N-terminal extension, reducing IGFBP binding by ~570-fold and extending half-life significantly vs. native IGF-1. Synthesized to >98% purity. Supplied for in-vitro and laboratory research use only.
an insulin-like growth factor for anabolic + cell proliferation research.
Purity>98% by HPLC
FormLyophilized powder
Endotoxin<1 EU/mg
Storage−20°C · 28 days reconstituted
TestingThird-party verified · USA synthesized
FYIResearch Use Only · Not for human use
IGF-1 LR3 has been extensively studied in muscle and metabolic research contexts:
- Prolonged receptor activation vs. native IGF-1 due to reduced binding protein affinity in animal models
- Stimulates satellite cell proliferation and myofibril hypertrophy in skeletal muscle tissue studies
- Upregulates protein synthesis via PI3K/Akt/mTOR signaling in preclinical research
- Enhances glucose uptake in muscle cells independent of insulin in cell culture models
- Half-life reported at ~20–30 hours vs. ~12 minutes for native IGF-1 in preclinical studies
Every batch is independently tested by a US-based third-party laboratory. Our Certificate of Analysis confirms:
Search COA Library →
- Identity: confirmed by HPLC and mass spectrometry
- Purity: >98% by HPLC
- Endotoxin: <1 EU/mg
- Appearance: white to off-white lyophilized powder
Search COA Library →
- Baserga R. (1994). The insulin-like growth factor I receptor: a key to tumor growth? Cancer Res.
- Buerge M, et al. (2010). Increased anabolic signaling with IGF-1 LR3 in skeletal muscle. J Appl Physiol.
- Rinderknecht E, Humbel RE. (1978). The amino acid sequence of human insulin-like growth factor I. J Biol Chem.
Support
common questions.
Everything you need to know about IGF-1 LR3 for your research. Can't find an answer? Contact our team directly.
IGF-1 LR3 (Long R3 IGF-1) is a recombinant analogue with two key structural differences from native IGF-1: an arginine-to-glycine substitution at position 3 (reducing IGFBP binding affinity by ~570-fold) and a 13-amino acid N-terminal extension. These modifications significantly extend its half-life and potency in preclinical models, making it a preferred tool for in-vitro research applications requiring sustained receptor activation.
Each vial contains 1mg of lyophilized IGF-1 LR3 powder. Reconstitute with bacteriostatic water (BAC Water) to your desired research concentration. We recommend 0.1–1.0 mL BAC Water per vial depending on your protocol, yielding 1–10 mg/mL solutions.
No. All products sold by Clean Labs USA are strictly for laboratory and in-vitro research use only. They are not drugs, supplements, or food products and are not intended for self-administration or therapeutic use. Purchase constitutes agreement to our Research Use Only terms.
Every order ships with a batch-specific COA. Search our full library at trycleanlabs.com/coa-library. COAs include HPLC purity data, mass spec identity confirmation, and endotoxin results.
Store lyophilized powder at −20°C in a sealed vial, away from light and moisture. Shelf life exceeds 24 months under these conditions. Once reconstituted, store at 4°C and use within 28 days. Avoid repeated freeze-thaw cycles of reconstituted solution.
shop by category.
Clean Labs USA
the standard for research integrity.
Every compound we carry is synthesized to research-grade standards, third-party verified for purity, and shipped with a full certificate of analysis.
igf-1 lr3