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nad+
NAD+ is a fundamental coenzyme required for over 500 enzymatic reactions, sirtuin activation, and DNA repair pathways. Supplied as pharmaceutical-grade lyophilized powder at >98% purity for cellular energy and longevity research. Not for human consumption.
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Research Use Only — Not for Human Consumption
NAD+ is one of the most studied coenzymes in longevity and metabolic research:
- Essential cofactor for sirtuin deacylases (SIRT1–7) — regulators of gene expression, metabolism, and aging in preclinical models
- Required substrate for PARP enzymes involved in DNA strand break repair in cell culture studies
- Supports mitochondrial biogenesis via PGC-1α activation in rodent models
- Circulating NAD+ levels decline ~50% between ages 40–60 in human observational studies
- IV and systemic NAD+ studied for neuroprotection, addiction, and metabolic syndrome in clinical research
Every batch is independently tested by a US-based third-party laboratory. Our Certificate of Analysis confirms:
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- Identity: confirmed by HPLC and mass spectrometry
- Purity: >98% by HPLC
- Endotoxin: <1 EU/mg
- Appearance: white to off-white lyophilized powder
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- Verdin E. (2015). NAD+ in aging, metabolism, and neurodegeneration. Science. 350(6265):1208–1213.
- Imai S, Guarente L. (2014). NAD+ and sirtuins in aging and disease. Trends Cell Biol. 24(8):464–471.
- Rajman L, et al. (2018). Therapeutic potential of NAD-boosting molecules. Cell Metab. 27(3):529–547.
Frequently Paired Compounds
GHK-Cu
Copper Peptide
Glutathione
Master Antioxidant
BAC Water
Reconstitution Solution
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nad+
coenzyme · longevity molecule
NAD+ (Nicotinamide Adenine Dinucleotide) is a coenzyme present in every living cell, required for over 500 enzymatic reactions. Supplied as pharmaceutical-grade lyophilized powder at >98% purity, synthesized in a US-based cGMP facility. Every batch independently tested and COA published publicly. Supplied for in-vitro and laboratory research use only.
a longevity coenzyme for cellular energy + metabolic research.
Purity>98% by HPLC
FormLyophilized powder
Endotoxin<1 EU/mg
Storage−20°C · use promptly reconstituted
TestingThird-party verified · USA synthesized
FYIResearch Use Only · Not for human use
NAD+ is one of the most studied coenzymes in longevity and metabolic research:
- Essential cofactor for sirtuin deacylases (SIRT1–7) — regulators of gene expression, metabolism, and aging in preclinical models
- Required substrate for PARP enzymes involved in DNA strand break repair in cell culture studies
- Supports mitochondrial biogenesis via PGC-1α activation in rodent models
- Circulating NAD+ levels decline ~50% between ages 40–60 in human observational studies
- IV and systemic NAD+ studied for neuroprotection, addiction, and metabolic syndrome in clinical research
Every batch is independently tested by a US-based third-party laboratory. Our Certificate of Analysis confirms:
Search COA Library →
- Identity: confirmed by HPLC and mass spectrometry
- Purity: >98% by HPLC
- Endotoxin: <1 EU/mg
- Appearance: white to off-white lyophilized powder
Search COA Library →
- Verdin E. (2015). NAD+ in aging, metabolism, and neurodegeneration. Science. 350(6265):1208–1213.
- Imai S, Guarente L. (2014). NAD+ and sirtuins in aging and disease. Trends Cell Biol. 24(8):464–471.
- Rajman L, et al. (2018). Therapeutic potential of NAD-boosting molecules. Cell Metab. 27(3):529–547.
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common questions.
Everything you need to know about NAD+ for your research. Can't find an answer? Contact our team directly.
NAD+ (Nicotinamide Adenine Dinucleotide) is a coenzyme present in every living cell. It is required for over 500 enzymatic reactions — most critically glycolysis, the TCA cycle, oxidative phosphorylation, and the activity of sirtuins and PARPs. Research interest has surged due to its central role in aging biology, with NAD+ levels shown to decline significantly with age in multiple model organisms including mice and humans.
NMN (Nicotinamide Mononucleotide) and NR (Nicotinamide Riboside) are precursors to NAD+ that are converted intracellularly. Systemic or IV NAD+ bypasses this conversion step and delivers the coenzyme directly. For in-vitro cell culture research, NAD+ is the direct substrate. Precursor molecules are generally preferred for oral bioavailability studies; NAD+ itself is preferred for systemic and cellular research protocols.
No. All products sold by Clean Labs USA are strictly for laboratory and in-vitro research use only. They are not drugs, supplements, or food products and are not intended for self-administration or therapeutic use. Purchase constitutes agreement to our Research Use Only terms.
Every order ships with a batch-specific COA. Search our full library at trycleanlabs.com/coa-library. COAs include HPLC purity data, mass spec identity confirmation, and endotoxin results.
Store lyophilized powder at −20°C in a sealed vial, away from light and moisture. NAD+ is sensitive to oxidation — keep sealed until use. Shelf life exceeds 24 months under these conditions. Once reconstituted, use promptly; do not store reconstituted solution for extended periods.
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Every compound we carry is synthesized to research-grade standards, third-party verified for purity, and shipped with a full certificate of analysis.
nad+